The drug Zocor is a lipid-lowering drug. The active substance of the drug is simvastatin. It is its metabolites that contribute to the process of inhibiting HMG-COA reductase. Simvastatin allows us to avoid the accumulation in the body of a token stream.
The drug reduces the level of cholesterol in the blood. Also, it helps to normalize the number of lipoproteins in the blood. Clinical studies show that patients achieve a positive effect after 2-3 weeks of taking the drug. A significant decrease in cholesterol levels is observed after 4-5 weeks of taking the drug. The medication allows you to maintain the allowable amount of cholesterol in the course of course administration. That is, the therapeutic effect is achieved only by the constancy of taking Zocor.
Zocor – a compound that includes simvastatin. Tablets have an oval shape and are covered with a mustard-colored shell. Zocor is sold only by prescription. The dosage of the drug is 10, 20, 40 mg.
What is Zocor (Simvastatin)?
Indications for use of Zocor
- The high content of cholesterol in the blood;
- High risk of heart failure;
- Heart failure on the background of diabetes mellitus;
- Exacerbation of atherosclerosis;
- Diagnosed stroke or heart attack;
- Genetic predisposition to hypercholesterolemia.
The main indications for the use of the medicinal product:
According to clinical studies, patients with diabetes mellitus note a decrease in the amount of sugar in the blood, while taking the drug. Also, it allows you to minimize the risk of serious complications after suffering a heart attack and stroke.
Contraindications to use
Mandatory contraindications that suggest that the medication should not be taken:
- Intolerance to the composition of the drug;
- Allergic reaction to lactose;
- Development of liver failure;
- Pregnancy and lactation;
- The patient is less than 10 years old;
- Renal failure.
Under no circumstances should you take alcohol during treatment with Zocor.
Development of side effects
Most often, doctors face such complaints as:
- Frequent constipation;
- Diarrhea after eating;
- Weakness and signs of asthenia;
- Convulsive syndrome;
- Rashes on the skin.
Methods of taking the drug and dosage
Zocor is taken regardless of food intake. It is recommended to wash down the tablet with a large glass of warm water. The daily rate of tablets is taken in the evening. The daily norm of the drug is from 5 to 80 mg. The norm is prescribed by the doctor.
The correct dosage is calculated by your doctor. The specialist takes into account medical history and clinical studies. Dosage adjustment is made after a month of taking the drug.
The dosage of Zocor is calculated taking into account the patient's disease.
Interaction with Drugs
It is not recommended to combine Zocor with nefazodone, ketoconazole, and erythromycin. The fact is that such combinations can lead to the development of the myopathic syndrome.
Taking the drug with medications such as diltiazem, cyclosporine, verapamil, contribute to the development of muscle tissue destruction syndrome. Zocor is also a catalyst for the enhanced activity of a drug based on anticoagulants.
During the reception of Zocor, it is necessary to refuse to use grapefruit juice. Joint reception can provoke an increase in the action of simvastatin.
Features of taking the drug
The effect of reducing the level of harmful cholesterol is enhanced in conjunction with proper nutrition and moderate exercise. In a severe form of hyperlipidemia, a specialist may prescribe a combined intake with several medications. The accuracy of the tablets must be also observed.
Taking the drug during pregnancy and lactation
Take Zocor during pregnancy, in any case, you can not. The fact is that it can have a critical impact on the development of the fetus. This can cause the development of diseases that will lead to the death of the fetus.
During lactation, you can also not take the drug. If taking pills is vital, you need to cancel lactation feeding and switch to mixtures.
Pediatricians do not recommend taking this drug for children who have not reached the age of 10 years. Girls can only take the drug if 1 year has passed since the beginning of regular menstruation.
Taking the drug for liver diseases
Metabolic processes of simvastatin occur in the liver. Therefore, recurrent liver diseases do not allow the drug to be included in the treatment process.
For kidney diseases
In severe kidney diseases, a minimum dosage of 10 mg is allowed. Constant monitoring by a doctor is required.
The price of the drug
The cost of the drug is affected by the number of tablets that are in the box. The price of Zocor depends on the country where the tablets are sold.
Before purchasing, you must check the expiration date. Zocor is not sold without a prescription. The pharmacist must require an official prescription, which is written by a doctor.
There are analogous medications in which the content of simvastatin is minimal, or this component is completely replaced with another.
List of active components that replace simvastatin:
Statin helps reduce the development of hyperlipidemia. Patients taking the medication say that after the end of taking Zocor, cholesterol returns to the same indicators as it was before the start of taking it. Experts recommend following a diet and physical therapy. This will help maintain the results that were achieved during treatment.
The drug Zocor is the active substance simvastatin. Metabolism develops in the liver cells. The drug is widely used for the treatment of atherosclerotic syndromes and the consequences of a heart attack or stroke.